Sashas Blend Joint Remedy for dogs and cats is a unique and potent combination of marine concentrates with high natural anti-inflammatory and joint-protective properties. Based on scientific research, the Sashas formula is the ideal choice for long-term joint support at both the earliest stages, and for advanced Degenerative Joint Disease .
Ongoing research on the Sashas™ formulation has demonstrated it:
1. Significantly inhibits PGE2 production (helps stop the production of the enzyme in the body responsible for pain) Sashas is a COX-2 inhibitor that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain.
2. Increases cartilage cell viability and decreases the loss of GAG’s from the cartilage matrix (keeps cartilage in the joints healthy)
3. Significantly inhibits Nitric Oxide production (helps stop the production of the enzyme in the body responsible for pain and the destruction of cartilage cells)
Many treatments only deal with resolving pain, but the underlying injury or disease continues to progress. Alternatively, other products are helpful in joint health but don’t deal with the pain.
In order to provide a complete joint treatment the product needs to:
1. Deal with pain and inflammation
2. Promote improved digestive function
3. Stimulate healthy joint function
4. Stimulate healthy joint fluid production to enable optimum uptake of nutrients (without this the result of any treatment may be impaired)
Sashas™ addresses all the key areas above, as well as the stimulation of healthy joint fluid production, which is important to filter the nutrients through the synovial membrane; without this the result of any treatment may be impaired.
SASHA’S BLEND KEY COMPONENTS, FUNCTIONS AND SOURCES
KEEPING JOINTS AND TISSUE HEALTHY AND STRONG
Hyaluronic Acid: THE primary compound that makes up Synovial Fluid.
Synovial fluid is responsible for reducing friction and cushioning within a joint, and for transporting nutrients into a joint and for removing waste/damaged elements from the joint.
HA is the primary building block for synovial fluid and cartilage, HA is found in the marine cartilage and green lipped mussel constituents of Sasha’s Blend.
Glucosaminoglycans Building blocks of new, healthy cartilage
Protects existing cartilage from degradation
Chondroitin Glucosaminoglycans are important constituents that the body uses in Dermatin the production of connective tissue (ligaments), to keep joint tissue Keratin hydrated, for the formation of synovial fluid (discussed above), and they are necessary for the body’s formation of cartilage and tendons. Chondroitin also has detoxifying effects.
Most supplements with which people are familiar contain glucosamine and/or chondroitin; Sasha’s blend contains those as well as keratin, dermatin and heparin which are all required within the body thus making Sasha’s Blend a far more complete supplement than most others.
MSM Helps protect, and is a building block of, soft tissues such as ligaments
Abalone and Green Lipped Mussel (GLM) ingredients of Sasha’s contain MSM.
REDUCING INFLAMMATION AND PAIN
Omega 3,9 Omega fatty acids 3,9, DHA and EPA contribute significant
Fatty Acids anti-inflammatory activity to joints.
Omega 3 fatty acids, in particular, inhibit inflammation by reducing the ability of Omega 6 to react with enzymes to create prostaglandins, which are a hormone-like compound that is known to cause inflammation and pain.
Green Lipped Mussel As well as supplying hyaluronic acid & glucosaminoglycans, Green Lipped Mussel (GLM), helps control pain. GLM directly inhibits the production of prostaglandin, which is a hormone-like substance that increases neural sensitivity to pain, thereby reducing pain significantly.
Green Lipped Mussel is a natural COX inhibitor. COX, or cyclo- oxygenase, is a necessary enzyme for the production of prostaglandins in the body. Prostaglandins increase neural sensitivity to the sensation of pain. By reducing the reactivity of COX, the production of prostaglandins is reduced so the pain sensation the body feels is significantly reduced. This is further aided by the presence of Omega 3 fatty acids which, as discussed above, further inhibit the formation of prostaglandins by inhibiting the ability of omega 6 fatty acids to react with any COX that is present.
Abalone: The abalone component of Sasha’s Blend targets and reduces the body’s own production of Nitric Oxide (NO) which, by itself, can cause the sensation of pain, but which partners with prostaglandin to cause significant increase in the sensation of pain.